一名4歲男孩患有1型神經(jīng)纖維瘤（NF1）、無癥狀的視神經(jīng)膠質(zhì)瘤和右側(cè)基底節(jié)T2高強(qiáng)度病變（圖A和圖B），在一年的時(shí)間內(nèi)出現(xiàn)左偏癱伴反射亢進(jìn)。神經(jīng)影像學(xué)顯示在他先前確定的T2高強(qiáng)度區(qū)域有一個(gè)類似囊腫的腫塊（圖，c和d）。雖然在沒有組織診斷的情況下很難區(qū)分T2高信號(hào)和低級(jí)別膠質(zhì)瘤，即使采用先進(jìn)的成像方法，T2高信號(hào)通常隨著年齡的增長而消失，并且不會(huì)變成囊性，伴有相關(guān)的占位效應(yīng)。再加上新的神經(jīng)癥狀的發(fā)展，這些核磁共振特征是令人擔(dān)憂的腫瘤患者的NF1。
圖：從2003年起，T2高信號(hào)在一個(gè)神經(jīng)纖維瘤病1型兒童腦磁共振成像（MRI）被發(fā)現(xiàn)，提示在右基底神經(jīng)節(jié)T2高信號(hào)，在神經(jīng)纖維瘤病1型兒童經(jīng)常被觀察到。
英文原文：
A 4-year-old boy with neurofibromatosis type 1 (NF1), anasymptomatic optic glioma, and a right basal ganglia T2-hyperintense lesion (figure, A andB) developed a lefthemiparesis with hyperreflexia over the course of a year. Neuroimaging revealeda cyst-like mass in the region of his previously identified T2 hyperintensity (figure, C andD). While it is oftendifficult to distinguish T2 hyperintensities from low-grade glioma withouttissue diagnosis,1 even with advanced imaging methods,2 T2 hyperintensities typically disappear with age and do notbecome cystic with associated mass effect. Coupled with the development of newneurologic signs, these MRI features are worrisome for neoplasm in a patientwith NF1.
Figure T2 hyperintensities in a child with neurofibromatosistype 1 Brain MRI from 2003 revealed a T2 hyperintensity in the right basalganglia, frequently observed in children with neurofibromatosis type 1.
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