另一邊，有人憂愁有人歡喜。1980年末才誕生的三氯蔗糖卻逃過了NutriNet-Santé的“代糖翻車報(bào)告”。1988年，安賽蜜被FDA批準(zhǔn)添加到食品當(dāng)中。它有沒有什么“罪證”呢？只能說截止目前，還沒有與它相關(guān)的癌癥發(fā)病報(bào)告。最后只剩那紐甜以及愛德萬甜了。這倆兄弟都來源于阿斯巴甜。不是它倆都對人體足夠安全，而是沒有專門的研究報(bào)告來證明它們的危害。看到這里，你可能發(fā)現(xiàn)了。人工甜味劑的流行歷史，糅合了糖業(yè)品牌的推動(dòng)、大眾追逐甜蜜的渴望、科研水平的限制。代糖能讓我們甜得很健康嗎？不一定。接二連三的反轉(zhuǎn)加反轉(zhuǎn)，玩的就像諜中諜一樣。只能說，代糖沒有表面那么單純。它對我們的身體，并不是真正地毫無影響！如果想放肆享用甜蜜，濫用代糖的話，可能我們也在走沉溺蔗糖的古人的老路子啊。公眾號(hào)有時(shí)內(nèi)容受限制，掃一掃DrX小助手進(jìn)群可以互相取暖。每周日晚徐醫(yī)生直播，解答大家關(guān)心的健康知識(shí)問題，平時(shí)還有定期紅包福利~ 參考資料：2022年8月26日，光明網(wǎng)Ronald K Kalkhoff, Marvin E Levin; The Saccharin Controversy. Diabetes Care 1 July 1978; 1 (4): 211–222.https://doi.org/10.2337/diacare.1.4.211I.C. Munro, B. Stavric and R. Lacombe, The current status of saccharin, in C.L. Winek (Ed.), Toxicology Annual 1974, Marcel Dekker, Inc., New York, 1975, p.71.B.T. Hunter, Consumer Beware! Your Food and What's Been Done To It, Bantam Press, New York, 1971, p. 319.Landrigan, P.J., Straif, K. Aspartame and cancer – new evidence for causation. Environ Health 20, 42 (2021). https://doi.org/10.1186/s12940-021-00725-ySoffritti M, Belpoggi F, Degli Esposti D, Lambertini L, Tibaldi E, Rigano A. First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environ Health Perspect. 2006;14(3):379–85. https://doi.org/10.1289/ehp.8711.Soffritti M, Belpoggi F, Tibaldi E, Degli Esposti D, Lauriola M. Life-span exposure to low doses of aspartame beginning during prenatal life increases Cancer effects in rats. Environ Health Perspect. 2007;115(9):1293–7. https://doi.org/10.1289/ehp.10271.Soffritti M, Belpoggi F, Manservigi M, Tibaldi E, Lauriola M, Falcioni L, et al. Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice. Am J Ind Med. 2010;53:1197–206. https://doi.org/10.1002/ajim.20896.Belpoggi F, Soffritti M, Padovani M, Degli Esposti D, Lauriola M, Minardi F. Results of long-term carcinogenicity bioassay on Sprague-Dawley rats exposed to aspartame administered in feed. Ann NY Acad Sci. 2006;1076:559–77. https://doi.org/10.1196/annals.1371.080.Lim U, Subar AF, Mouw T, Hartge P, Morton LM, Stolzenberg-Solomon R, et al. Consumption of aspartame-containing beverages and incidence of hematopoietic and brain malignancies. Cancer Epidemiol Biomark Prev. 2006;15(9):1654–9. https://doi.org/10.1158/1055-9965.EPI-06-0203Schernhammer ES, Bertrand KA, Birmann BM, Sampson S, Willett WC, Feskanich D. Consumption of artificial sweetener- and sugar-containing soda and risk of lymphoma and leukemia in men and women. Am J Clin Nutr. 2012;96(6):1419–28. https://doi.org/10.3945/ajcn.111.030833Marinovich M, Galli CL, Bosetti C, Gallus S, La Vecchia C. Aspartame, low-calorie sweeteners and disease: regulatory safety and epidemiological issues. Food and Chemical Toxicology 2013; 60:109–115Debras C, Chazelas E, Srour B, et al. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLoS Medicine 2022; 19(3):e1003950.Choudhary AK, Pretorius E. Revisiting the safety of aspartame [published correction appears in Nutr Rev. 2018 Apr 1;76(4):301] [published correction appears in Nutr Rev. 2018 Nov 1;76(11):860]. Nutr Rev. 2017;75(9):718-730. doi:10.1093/nutrit/nux035Bernadene A. Magnuson, Ashley Roberts, Earle R. Nestmann,Critical review of the current literature on the safety of sucralose,Food and Chemical Toxicology,Volume 106, Part A,2017,Pages 324-355,ISSN 0278-6915,https://doi.org/10.1016/j.fct.2楊遠(yuǎn)志,李發(fā)財(cái),帥斌,等.天然健康糖醇——赤蘚糖醇在低能量食品中的應(yīng)用[J].中國食品添加劑, 2013(1): 181-185.
