▎藥明康德內(nèi)容團(tuán)隊(duì)編輯
人體微生物組與我們共同進(jìn)化、共同生存,也與我們的健康有著復(fù)雜聯(lián)系。比如我們常說(shuō)的腸道菌群,其多樣性和構(gòu)成情況,對(duì)每個(gè)人來(lái)說(shuō)都是獨(dú)特的健康相關(guān)特征。而放眼消化道以外,人體不同組織內(nèi)的微生物與癌癥的關(guān)聯(lián),近年來(lái)也得到了更多探索。《柳葉刀-腫瘤學(xué)》7月刊上的一篇文章就針對(duì)這個(gè)有趣的主題,簡(jiǎn)要盤(pán)點(diǎn)了當(dāng)前研究進(jìn)展。
截圖來(lái)源:Lancet Oncology
預(yù)測(cè)免疫療法的療效
對(duì)常見(jiàn)化療的效果可能也有影響
腫瘤中也有微生物生長(zhǎng)
參考資料(可上下滑動(dòng)查看)
[1] Ashray Gunjur. (2020). Cancer and the microbiome. The Lancet Oncology, DOI: 10.1016/S1470-2045(20)30351-X
[2] Gopalakrishnan V, Spencer CN, Nezi L, et al. (2018). Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science, DOI: 10.1126/science.aan4236
[3] Microbiotica, Cancer Research UK and Cambridge University Hospitals collaborate in landmark cancer microbiome study. Retrieved July 21, 2020, from http://commercial.cancerresearchuk.org/microbiotica-cancer-research-uk-and-cambridge-university-hospitals-collaborate-landmark-cancer
[4] Ke W, Saba JA, Yao CH, et al. (2020). Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion. Nat Commun, DOI: 10.1038/s41467-020-16220-w
[5] Nejman D, Livyatan I, Fuks G, et al. (2020). The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science, DOI: 10.1126/science.aay9189
注:本文旨在介紹醫(yī)藥健康研究進(jìn)展,不是治療方案推薦。如需獲得治療方案指導(dǎo),請(qǐng)前往正規(guī)醫(yī)院就診。
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