上周我們對外泌體有關(guān)的研究進行了梳理，整理了今年新獲得自助的外泌體有關(guān)的國自然基金和必看的綜述（外泌體研究必看的經(jīng)典綜述），今天我們來看另外一個科研的熱點：腸道微生物。

關(guān)于腸道微生物，我們也寫過一些文章：

（文章篇）S5E02：從一篇Cell看腸道菌群研究模式

（文章篇）S5E17：神經(jīng)科學(xué)大牛的一篇Nature Medicine，腸道菌群與中風(fēng)的免疫學(xué)原因

（文章篇）S5E05: 來篇Science提提神，從免疫角度看宿主基因-腸道微生物作用

（文章篇）S5E03：宿主通過microRNA調(diào)控腸道微生物多樣性

腸道微生物研究入門必看：神奇菌群有哪些？

（策略篇）S5E1：腸道微生物，復(fù)古的科研新熱點！

腸道微生物作為熱點我們可以從2017年這一年發(fā)表的10以上的SCI文章上看出來：

共有252篇，最近的一篇是9月6號發(fā)表在Sci Trans Med雜志上的文章。

從今年剛公布的國自然基金來看，腸道菌群為主題的研究也確實是資助的重點，共資助285項，資助金額1.29億。其中青年基金108項，面上項目137項，地區(qū)項目34項，重點項目有6項，其中醫(yī)學(xué)部南京中醫(yī)藥大學(xué)戰(zhàn)麗彬獲得重點項目一項：

基于腸道菌群“從脾論治”疾病易感痰濕體質(zhì)的中醫(yī)治未病的生物學(xué)基礎(chǔ)研究 

下面我們就梳理下研究腸道微生物研究必看的經(jīng)典綜述（影響因子10+，按領(lǐng)域區(qū)分）：

一、菌群與腫瘤

1. Anticancer effects of the microbiome and its products.

2. Microbiota: a key orchestrator of cancer therapy.

3. Cancer and the gut microbiota: an unexpected link.

二、菌群與心血管代謝疾病

1. Gut Microbiota in Cardiovascular Health and Disease.

2. Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction.

3. Role of gut microbiota in atherosclerosis.

4. The gut microbiome, diet, and links to cardiometabolic and chronic disorders.

5. Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders.

6. The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases.

7.Beyond gut feelings: how the gut microbiota regulates blood pressure.

三、菌群與神經(jīng)系統(tǒng)疾病

1.Gut/brain axis and the microbiota .

2.The Central Nervous System and the Gut Microbiome.

3. Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals.

4. Interactions between the microbiota, immune and nervous systems in health and disease.

四、菌群與免疫

1. Dysbiosis and the immune system.

2. The microbiome and innate immunity.

3. The microbiota in adaptive immune homeostasis and disease.

4. Gut microbiota, metabolites and host immunity.

5.Understanding the Holobiont: How Microbial Metabolites Affect Human Health and Shape the Immune System.

6.How nutrition and the maternal microbiota shape the neonatal immune system.

五、菌群與消化系統(tǒng)疾病

1.Gut microbiome and liver diseases.

2. Gut-liver axis in alcoholic liver disease.

3. From Hype to Hope: The Gut Microbiota in Enteric Infectious Disease.

4. Diagnostic and Prognostic Microbial Biomarkers in Inflammatory Bowel Diseases.

5. Implications of microbiota and bile acid in liver injury and regeneration.

6. Changes in the Intestinal Microbiome and Alcoholic and Nonalcoholic Liver Diseases: Causes or Effects?.

六、菌群與呼吸系統(tǒng)疾病

1. Emerging pathogenic links between microbiota and the gut-lung axis.

2. Microbiota in allergy and asthma and the emerging relationship with the gut microbiome.

3. An integrative view of microbiome-host interactions in inflammatory bowel diseases.

七、菌群與內(nèi)分泌

Microbial endocrinology: the interplay between the microbiota and the endocrine system.