【Author】 WANG Wei-wei,ZHANG Hong-miao,ZHANG Ying,LI Jie-ru.Department of Cardiology, the Second Affiliated Hospital of Kunming Medical College,Kunming 060031,China
【機(jī)構(gòu)】 云南昆明醫(yī)學(xué)院第二附屬醫(yī)院干療心內(nèi)科;
【摘要】 目的探討老年高血壓患者高尿酸血癥與缺血性腦卒中發(fā)生的相關(guān)性。方法分析100例60歲以上老年原發(fā)性高血壓患者,根據(jù)尿酸水平分為對(duì)照組(尿酸≤417μmol/L,51例)和實(shí)驗(yàn)組(尿酸≥417μmol/L,49例),比較兩組血尿酸水平與缺血性腦卒中之間的關(guān)系。結(jié)果兩組在年齡、體質(zhì)指數(shù)(BMI)、飲酒史、糖尿病史等一般情況方面差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)。入院時(shí)的尿酸水平,吸煙史及腦卒中發(fā)生率差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。實(shí)驗(yàn)組不同時(shí)間段各組間尿酸和腦卒中嚴(yán)重程度評(píng)分均有統(tǒng)計(jì)學(xué)意義(P<0.05)。Logistic回歸分析發(fā)現(xiàn),調(diào)整腦卒中的其他危險(xiǎn)因素后,實(shí)驗(yàn)組的腦卒中的發(fā)生率是對(duì)照組的2.88倍(β=1.059,OR=2.884,P=0.03)。結(jié)論尿酸水平增高與老年原發(fā)性高血壓患者腦卒中發(fā)生密切相關(guān)。
【Abstract】 Objective To investigate the relationship between blood uric acid and ischemic stroke in the elderly with hypertension.Methods Totally 100 elderly patients with hypertension were divided into study group(blood uric acid≥417μmol/L,n=49) and control group(blood uric acid<417μmol/L,n=51).The relationship between the level of uric acid and ischemic stroke were analyzed in two groups.Results There were not significant differences in age,body mass index (BMI),smoking and drinking,diabetes(P>0.05... 更多
【Key words】 Hypertension; Uricacid; Ischemicstroke;
【分類號(hào)】R544.1; R743.3; R589.7;
【中文主題詞】高血壓*;卒中*;高尿酸血癥*;尿酸;病人;因素分析, 統(tǒng)計(jì)學(xué);對(duì)照組;統(tǒng)計(jì)學(xué);人體質(zhì)量指數(shù);Logistic模型
【英文主題詞】Hypertension*;Stroke*;Hyperuricemia*;Uric Acid;Patients;Factor Analysis, Statistical;Control Groups;Statistics;Body Mass Index;Logistic Models
【基金】 云南省教育廳科研基金(2010Y180)
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